Technology Available for Licensing
Bioinformatics
Childrens Hospital Los Angeles Ref. Number: 2007-002
Title: Sparse representation and Bayesian detection of genome copy number changes from array data
Principal Investigator: Dr. Shahab Asgharzadeh
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 008.0
Title: Fenretinide Combinations
Principal Investigators: Patrick Reynolds , Barry Maurer
Patents: 6,352,844, 6,368,831 , CA, EP, JP, BR, CN, HK, IN, MX
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 028.0
Title: PPMP Use and Composition of Matter
Principal Investigators: Patrick Reynolds , Barry Maurer
Patents: 10/712,763
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 022.0
Title: Fenretinide Compositions with Increased Bioavailability and Ease of Administration
Principal Investigators: Patrick Reynolds , Barry Maurer
Patents: 10/010,914 , EP, JP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 025.0
Title: Pharmaceutical Compositions of Safingol and Methods of Using the Same
Principal Investigators: Patrick Reynolds , Barry Maurer
Patents: 10/782,459 , CA, JP, MX, EP (DE, IT, UK, FR, FP)
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 027.0
Title: Lym-X-Sorb Powder Formulations
Principal Investigators: Patrick Reynolds , Barry Maurer
Patents: 10/767,352, 11/170,371, 11/170,561 , JP, MX, EP, CA
Detailed non-confidential summary
Cardiovascular and Pulmonary Hypertension
Childrens Hospital Los Angeles Ref. Number: 019.0
Title: Methods of facilitating vascular growth in cardiac muscle and methods for the production of recombinant EMAP II.
Principal Investigator: Margaret Schwarz
Patents: US Application No. 09/733,306
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 018.0
Title: Methods and pharmaceutical formulations for the treatment of pulmonary hypertension and methods for screening compounds useful in the treatment of pulmonary hypertension
Principal Investigator(s): Margaret Schwarz
Patents: US Application 10/274,788 , CA, EP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 010.0
Title: Methods for Facilitating Vascular Growth
Principal Investigator(s): Margaret Schwarz
Patents: US Patent # 6,306,612, US Patent #6,857,749 , AU, CA, EP, JP
Detailed non-confidential summary
Developmental Biology, Tissue Repair and Regeneration
Childrens Hospital Los Angeles Ref. Number: 024.0
Title: Treatment and prevention of abnormal scar formation
Principal Investigator(s): Tai-Lan Tuan and David Warburton
Patents: US application No. 10/439,267 , JP, EP, BR, SG, CN
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: Title: Bone Morphogenic Protein (BMP) inhibitor for use in regulating important developmental and disease processes
Principal Investigator(s): Wei Shi and David Warburton
Patents: PCT application filed
Detailed non-confidential summary
Diagnostic Tests
Childrens Hospital Los Angeles Ref. Number: 2007-001
Title: Molecular Diagnosis of Brain Glial Tumors
Principal Investigator: Dr. Hae-Ri Song
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 2007-004
Title: Mitochondrial DNA polymorphisms are associated with functional disease
Principal Investigator: Richard Boles
Non-confidential summary
DIMSCAN: automated technology for screening anti-cancer agents
Childrens Hospital Los Angeles Ref. Number: 005.0
Title: Fluorescence Digital Imaging Microscopy System
Principal Investigator: Patrick Reynolds
Patents: 08/622,110, 6,459,805, 6,665,430
Detailed non-confidential summary
Mol Cancer Ther2007;6(3). March 2007
Non-Invasive Real-Time Analyte Monitoring
Childrens Hospital Los Angeles Ref. Number: 007.0
Title: Non-Invasive Glucose Monitor
Principal Investigator: Mark Borchert
Patents: 6,181,957, 6,424,850 , CA, MX, EP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 023.0
Title: Non-Invasive Identification and Measurement of Selected Toxins or Substances in the Human Body
Principal Investigator: Mark Borchert
Patents: 6,574,501, 6,961,599, 10/396,035 , CA, EP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 006.0
Title: Non-Invasive Intracranial Pressure Monitor
Principal Investigator: Mark Borchert
Patents: 6,129,682 , JP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 026.0
Title: Measurement of Macular Pigments
Principal Investigator: Mark Borchert
Patents: 10/773,099 , CA, EP
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 013.0
Title: Visual Acuity and Ambyopia Screening device
Principal Investigator: Mark Borchert
Patents: 6,402,320
Detailed non-confidential summary
Research Tools
Childrens Hospital Los Angeles Ref. Number: 2007-008
Title: "Transgenic Mouse Model for Medulloblastoma"
Principal Investigator: Gregory Shackleford
Stem Cell Biology and Gene Therapy
Childrens Hospital Los Angeles Ref. Number: 012.0
Title: Gene therapy by administration of genetically engineered
CD34.sup.+ cells obtained from cord blood
Principal Investigator: Donald B. Kohn
Patents: 6,984,379
Detailed non-confidential summary
Childrens Hospital Los Angeles Ref. Number: 030.0
Title: Minimal Lentiviral Vector System
Principal Investigator: Paula Cannon
Patents: US application No. 11/003,967 and PCT application
Detailed non-confidential summary
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