Neuroscience
Director: Richard B. Simerly, PhD
Accomplishments
Clinical Research
In the last year the clinical research component has produced 53 peer-reviewed research studies and 21 non-peer-reviewed contributions. Important successes include those of:
- Virdette Brumm, PhD, who received a Junior Faculty Academic Career Development Award and the USC Health Sciences Women’s Faculty Association Research Award
- Wendy Mitchell, MD, who has received three pharmaceutical industry awards, three GCRC funded awards for ongoing studies, a contract from Westat (NICHD) for an ongoing study of pediatric HIV, and she sits on an NIH study section
- Rex A. Moats, PhD, is involved in studies of brain tumor growth inhibition by an integrin antagonist and a gene associated with premature suture closure in craniosynostosis
- Stefan Bluml, PhD, has received an NIH grant to study the relationships between MR spectroscopic findings and the childhood brain tumor factoring system developed by FH Gilles and colleagues. He continues his studies of cerebral metabolic estimation in MR spectroscopy
- Stephan Erberich, PhD, and Dr. Brumm are doing functional imaging studies of frontal lobe executive functioning in brain damaged children
- Mark Borchert, MD, continues studies of aqueous glucose concentration in the anterior chamber of the eye
- Lan S. Chen, MD, runs studies in peripheral autonomic nervous plasticity in cardiac damage, in cortical seizure propagation, and in seizure propagation in rat brain slices; Robert S. Snodgrass, MD, continues his studies of compliance with antiseizure medication in childhood
- Susan Turkel, MD, continues her studies of depression in children with medical illness, and her studies of delirium
- Richard Boles, MD, continues his studies of mitochondrial DNA
- Douglas Hyder, MD, continues his role with the COG in studies of children with brain tumors
- Drs. Gordon McComb and Michael Levy continue their neurosurgical studies
Laboratory Research
The Childrens Hospital Los Angeles Research Institute's Developmental Neurobiology Program, is being assembled by the joint efforts of many individuals at Childrens Hospital and at USC. We have reached an agreement with the University of Southern California to develop a USC Graduate Program in Developmental Neurobiology on the Childrens Hospital Los Angeles campus.
Members
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Investigator
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Title
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Interest
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Boles, Richard MD
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Asst. Professor Pediatrics
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Mitochondrial abnormalities - genetic neurology
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Bluml, Stefan PhD
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Asst. Professor Radiology
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Magnetic spectroscopy of brain
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Borchert, Mark MD
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Assoc. Professor Ophthalmology
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Non-Invasive technology in neuroophthalmology
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Brumm, Virdette, PhD
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Asst. Prof. Neurology & Pediatrics
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Executive functioning in ADHD Children & Functional Imaging
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Chen, Lan MD
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Assoc. Professor Neurology
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Dynamic Seizure Focus Mapping and Implantable seizure detection microchips
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Erberich, Stephan, PhD
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Asst. Prof. Research Radiology
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Brain tumor quantitation; forebrain angiogenesis
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Gonzalez-Gomez, Ignacio MD
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Asst. Professor Pathology
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Brain tumor quantitation; forebrain angiogenesis
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Jacobson, Julienne MD
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Asst. Professor Psychiatry
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Childhood mood disorders and psychopharmacology
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Krieger, Mark MD
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Asst. Professor Neurosurgery
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Neurosurgery: Hydrocephalus and visualization
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McComb, Gordon MD
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Professor, Neurosurgery
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Neurosurgery: Hydrocephalus and visualization
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Mitchell, Wendy MD
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Prof. Neurology
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Genetic neurology; antiepileptic drug evaluation
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Moats, Rex A. PhD
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Asst. Prof. Pathology and Radiology
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Cellular, functional and molecular imaging
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Nelson, Marvin D. Jr., MD
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Professor Radiology
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Molecular and functional imaging
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Rosol, Michael PhD
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Asst. Professor Radiology
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In vivo optical and micro-CT imaging
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Tsent-Ong, Linda MD
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Asst. Professor Neurology
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Pediatric Neuromuscular Disease and Phosphorus spectroscopy
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